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Table 1 Patient characteristics of Low (< 25 cc) vs High (> 25 cc) tumor burden

From: Relationship between hepatocellular carcinoma circulating tumor cells and tumor volume

 

Low tumor burden

High tumor burden

p

Samples/Patients

11/11

13/11

 

Age, years (median, [range])

67.3 [43.4–78.9]

70.7 [50.2–82.7]

0.21

Gender (M/F)

10/1

9/2

0.99

ECOG

0.99

 0

4

6

 

 1

4

5

 2

1

2

 3

1

0

Cause of cirrhosis

0.36

 Alcohol

5

2

 

 HBV/HCV

2

2

 NASH

1

4

 Other

3

3

Labs at CTC draw (median, [range])

 Total bilirubin, mg/dL

1.0 [0.5–3.7]

0.85 [0.4–2.4]

0.15

 Albumin, g/dL

4.1 [3.0–4.9]

3.95 [3.0–4.7]

0.58

 Platelets, 103/μL

123 [61–208]

200 [69–493]

0.04

 INR

1.2 [1.0–1.4]

1.1 [0.9–1.4]

0.23

 Creatinine, mg/dL

1.00 [0.76–1.29]

0.99 [0.69–1.83]

0.85

 AFP, ng/mL

9.1 [1.5–9524]

69 [2.2–132,367]

0.18

  1. Note data for age, ECOG status, and labs were done at the time of CTC analysis
  2. p value < 0.05 considered significant and bold italicized in table
  3. p value for ordinal data (age and labs) were done using the Mann-Whitney test
  4. p value for categorical data was done by Fisher Exact (gender, ECOG, cause of cirrhosis). ECOG 0–1 vs 2–3 and cause of cirrhosis alcohol vs all other causes were compared
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Cancer Convergence

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