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Table 1 Patient characteristics of Low (< 25 cc) vs High (> 25 cc) tumor burden

From: Relationship between hepatocellular carcinoma circulating tumor cells and tumor volume

  Low tumor burden High tumor burden p
Samples/Patients 11/11 13/11  
Age, years (median, [range]) 67.3 [43.4–78.9] 70.7 [50.2–82.7] 0.21
Gender (M/F) 10/1 9/2 0.99
ECOG 0.99
 0 4 6  
 1 4 5
 2 1 2
 3 1 0
Cause of cirrhosis 0.36
 Alcohol 5 2  
 HBV/HCV 2 2
 NASH 1 4
 Other 3 3
Labs at CTC draw (median, [range])
 Total bilirubin, mg/dL 1.0 [0.5–3.7] 0.85 [0.4–2.4] 0.15
 Albumin, g/dL 4.1 [3.0–4.9] 3.95 [3.0–4.7] 0.58
 Platelets, 103/μL 123 [61–208] 200 [69–493] 0.04
 INR 1.2 [1.0–1.4] 1.1 [0.9–1.4] 0.23
 Creatinine, mg/dL 1.00 [0.76–1.29] 0.99 [0.69–1.83] 0.85
 AFP, ng/mL 9.1 [1.5–9524] 69 [2.2–132,367] 0.18
  1. Note data for age, ECOG status, and labs were done at the time of CTC analysis
  2. p value < 0.05 considered significant and bold italicized in table
  3. p value for ordinal data (age and labs) were done using the Mann-Whitney test
  4. p value for categorical data was done by Fisher Exact (gender, ECOG, cause of cirrhosis). ECOG 0–1 vs 2–3 and cause of cirrhosis alcohol vs all other causes were compared